Selank – 10 mg

Selank – Research Grade

For Research Use Only. Not intended for human consumption.

Selank is a synthetic heptapeptide analogue of the endogenous immunomodulatory peptide tuftsin (Thr-Lys-Pro-Arg). Developed by the Institute of Molecular Genetics of the Russian Academy of Sciences, Selank has been extensively studied for its anxiolytic, nootropic, and immunomodulatory properties in preclinical and clinical research settings. Its stability and resistance to enzymatic degradation make it a well-suited candidate for peptide research involving the central nervous system and immune function.

Compound Details

• Sequence: Thr-Lys-Pro-Arg-Pro-Gly-Pro
• Molecular Formula: C₃″H₆₁N₁₅O₁₂
• Molecular Weight: 751.9 g/mol
• CAS Number: 129954-34-3
• Purity: ≥98% (HPLC)
• Form: Lyophilized powder
• Storage: Store at -20°C, away from light and moisture

Key Benefits

• Anxiolytic Activity: Selank has been studied extensively for its ability to reduce anxiety-like behavior in animal models without the sedative or dependency-forming effects associated with benzodiazepines. It is believed to modulate GABAergic and serotonergic signaling pathways.
• Nootropic & Cognitive Enhancement: Research has demonstrated Selank’s potential to enhance memory consolidation, learning, and attention in preclinical models. It is thought to influence BDNF (brain-derived neurotrophic factor) expression and enkephalin metabolism.
• Immunomodulation: As a tuftsin analogue, Selank has been shown to modulate the activity of T-cells, natural killer cells, and macrophages in research models, supporting its study in immune regulation and inflammatory response research.
• Stress Response Regulation: Studies suggest Selank can normalize stress-induced changes in gene expression and neurotransmitter balance, making it a subject of interest in HPA axis and neuroendocrine stress research.
• Neuroprotection: Selank has been investigated for its potential neuroprotective effects, including the ability to stabilize enkephalins — endogenous opioid peptides involved in mood and pain regulation — by inhibiting their enzymatic breakdown.
• Anti-Inflammatory Properties: Preclinical research has explored Selank’s role in downregulating pro-inflammatory cytokines such as IL-6 and TNF-α, positioning it as a candidate for neuroinflammation and systemic inflammation studies.
• Metabolic Stability: Unlike many peptides, Selank demonstrates resistance to peptidase degradation, giving it a longer effective research window and making it practical for in vivo study designs.

Handling & Reconstitution

For laboratory use, reconstitute in sterile bacteriostatic water or an appropriate solvent per your research protocol. Handle in accordance with standard laboratory safety procedures.

This product is intended solely for in vitro research and laboratory use. It is not approved by the FDA for human or veterinary use. All research must comply with applicable regulations.